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WHO LIBRARY DIGEST FOR AFRICA
No. 61, July - August 1999
(Last Revised on 3/10/99)

Table of Contents:

1.0  Introduction
2.0  Recent WHO press releases
3.0  New WHO publications from HQ
4.0  Information from recent WHO periodicals
5.0  Information from WHO-produced newsletters
6.0  New WHO documents

1.0 Introduction

The 49th session of the Regional Committee of the WHO African Region has just finished in Windhoek, Namibia. Dr Samba was re-elected as Regional Director for a further period of 4 years.

Eight Resolutions were passed and included:

  • the Regional strategy for mental health
  • Essential drugs
  • the Integrated management of childhood illness
  • a Review of the implementation of the Bamako Initiative
  • Health sector reform
  • the Regional Health-for-All policy for the 21st century.

The Annual report of the WHO AFRO Regional Director on the work in the African Region for 1998 was presented at the Regional Committee and can be requested from the AFRO Office in Harare (see address at end of List of documents)

The 50th session of the Regional Committee will take place in 2000 in Ouagadougou, Burkina Faso.

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2.0 Recent  WHO Press Releases

2.1 Despite fighting and electricity cuts, the campaign to vaccinate children against polio in the Democratic Republic of Congo (DRC) successfully reached 8.2 million of the country’s 10 million children under five, according to early reports from the WHO and UNICEF, which spearheaded the campaign there. The figure should be closer to 9 million once complete data is received, said officials.

Over 75,000 volunteer vaccinators delivered polio vaccine to children over a three-day period (13-15 August) in the first of three rounds of National Immunization Days in DRC. Fighting stopped in nine-tenths of the country to allow the campaign to go ahead, following the intervention of the UN secretary-General Mr Kofi Annan, urging all sides to comply with truces for polio immunization.

DRC is the single biggest priority for the global effort to eradicate polio with the most intense virus transmission in the world. Over 16,000 health stations were set up throughout the country to vaccinate children during the campaign. (Press Release WHO/43, 20 August 1999)

2.2 The WHO has released a new version of the International Classification of Functioning and Disability (Beta-2 version of ICIDH-2) for field trials. This is the last version to be tested and commented on throughout the world before it is finalized and submitted to the World Health Assembly in 2001. Field trials are due to finish in July 2000 and this version is open for comments by all individuals and organizations, including via the web from the WHO website.

This classification, originally developed in 1980 as a manual for consequences of disease, complements the International Classification of Diseases (ICD-10) and now deals with functional states (i.e., mobility, social integration, etc.) associated with health conditions. It recognises the fact that a diagnosis of diseases and disorders, while important for clinical and public health needs, is not sufficient to describe the functional status of the individual and also to predict, guide and plan the various needs of such an individual.(Note for the Press no. 19, 20 August 1999)

2.3 Sunlight, an essential prerequisite for life, may be extremely dangerous to human health. Excessive exposure to the sun is known to be associated with increased risks of various skin cancers, cataracts and other eye diseases, as well as accelerated skin ageing. It may also adversely affect people’s ability to resist infectious diseases, and compromise the effectiveness of vaccination programmes.(Revised Fact Sheet no. 227, 3 August 1999)

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3.0 New WHO Publications from Headquarters

3.1 Teaching health statistics : lesson and seminar outlines, by S.K. Lwanga, Cho-Yook Tye, O. Ayeni. 2nd ed. 1999. 230p. ISBN 9241545186
Price in developing countries: Swfr. 50.40
The topics covered form an internationally applicable basic curriculum for teaching health statistics to trainee health workers, which can be adapted to meet the needs of different groups of students. The book includes not only the conventional topics of data collection, presentation and analysis, probability and vital statistics but also health indicators, use of computers and rapid methods of interim assessment. It is not intended for use by students for self-instruction.
 
3.2 Safe management of wastes from health-care activities, edited by A. Pruss, E. Giroult and P. Rushbrook. 1999, 230p. ISBN 9241545259
Price in developing countries Swfr.50.40
The waste produced in the courses of health-care activities, from contaminated needles to radioactive isotopes, carries a greater potential for causing infection and injury than any other type of waste, and inadequate or inappropriate management is likely to have serious public health consequences and deleterious effects on the environment. The handbook pays particular attention to basic processes and technologies that are not only safe but also affordable, sustainable and culturally appropriate.
 
3.3 Environmental Health Services in Europe. Guidance on the development of education and training curricula, by Martin Fitzpatrick and Xavier Bonnefoy. (WHO Regional Publications, European Series no. 84) WHO Regional Office for Europe. Copenhagen, Denmark. 1999, 198p. ISBN 9289013508
Price: Swfr 45.-
The WHO Regional Office for Europe has been deeply involved in working with its Member States in producing a wide range of guidance instruments to assist them in reforming their environmental health services and developing their capacities in environmental health management.
 
3.4 Sustainable Development and Health for all : building the capacity of national health authorities. (WHO Regional Publication, South-East Asia Series no. 30) WHO Regional Office for South-East Asia. New Delhi, India. 1999, 83p. ISBN 9290222134
To obtain a free copy of this publication, please contact WHO/SEARO, World Health House, Indraprastha Estate, Mahatma Gandhi Road, New Delhi 110002, India.
While the health sector in most countries has the responsibility to promote health, it often finds itself handicapped in actually moving the levers to make health happen. This is so because health is not merely a medical issue, but a much wider concept of social well-being. Policy-makers in the national health sector, and those in related development sectors, should find the new insights provided by the author of immense value.

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4. Information from Recent WHO Periodicals

4.1 Bulletin of the World Health Organization, 1999, 77(7)

Lessons on humanitarian assistance, by Miguel Gracia-Antequera and Maria Morales Suarez-Varela. pp.607-609.

Conflict almost completely destroyed Rwanda’s infrastructure in 1994. Natural disasters, as well as disasters caused by humans, have severely challenged humanitarian aid available within the country. In this study, we have analysed the experiences of nongovernmental organizations since the summer of 1994 to evaluate how these difficulties may be overcome. One of the problems identified has been the restrictions on the ability to introduce effective health planning due to the poor quality of available local information. The implementation of effective plans that show due consideration to the environment and society is clearly necessary. Effective monitoring and detailed observation are identified as being essential to the continuity of existing humanitarian assistance.

Integrated management of childhood illness : a summary of first experiences
T. Lambrechts, J. Bryce and V. Orinda. pp. 582-594.
The strategy of Integrated Management of Childhood Illness (IMCI) aims to reduce child mortality and morbidity in developing countries by combining improved management of common childhood illnesses with proper nutrition and immunization. The strategy includes interventions to improve the skills of health workers, the health system, and family and community practices. This article describes the experience of the first countries to adopt and implement the IMCI interventions, the clinical guidelines dealing with the major causes of morbidity and mortality in children, and the training package on these guidelines for health workers in first-level health facilities. The most relevant lessons learned and how these lessons have served as a basis for developing a broader IMCI strategy are described.
 
Evaluation of a rapid and inexpensive dipstick assay for the diagnosis of Plasmodium falciparum malaria
C. D. Mills, et al. pp. 553-559.
Rapid, accurate and affordable methods are needed for the diagnosis of malaria. Reported here is an evaluation of a new immunochromatographic strip, the PATH Falciparum Malaria IC Strip, which is impregnated with an immobilized IgM monoclonal antibody that binds to the HRP-II antigen of Plasmodium falciparum. In contrast to other commercially available kits marketed for the rapid diagnosis of falciparum malaria, this kit should be affordable in the malaria-endemic world. Using microscopy and polymerase chain reaction (PCR)-based methods as reference standards, we compared two versions of the PATH test for the detection of P. Falciparum infection in 200 febrile travellers. As determined by PCR and microscopy, 148 travellers had malaria, 50 of whom (33.8%) were infected with P. Falciparum. Compared with PCR, the two versions of the PATH test had initial sensitivities of 90% and 88% and specificities of 97% and 96%, respectively, for the detection of falciparum malaria. When discrepant samples were retested blindly with a modified procedure (increased sample volume and longer washing step) the sensitivity and specificity of both kits improved to 96% and 99%, respectively. The two remaining false negatives occurred in samples with more than 100 parasites per miu-l of blood. The accuracy, simplicity and predicted low cost may make this test a useful diagnostic tool in malaria-endemic areas.
 
Health inequalities and social group differences : what should we measure?
C. J. L. Murray, E. E. Gakidou and J. Frenk. pp. 537-543.
Both health inequalities and social group differences are important aspects of measuring population health. Despite widespread recognition of their magnitude in many high- and low-income countries, there is considerable debate about the meaning and measurement of health inequalities, social group health differences and inequities. The lack of standard definitions, measurement strategies and indicators has and will continue to limit comparisons - between and within countries, and over time - of health inequalities, and perhaps more importantly comparative analyses of their determinants. Such comparative work, however, will be essential to find effective policies for governments to reduce health inequalities. This article addresses the question of whether we should be measuring health inequalities or social group health differences. To help clarify the strengths and weaknesses of these two approaches, we review some of the major arguments for and against each of them.

4.2 WEEKLY EPIDEMIOLOGICAL RECORD

Tuberculosis control : progress in 1995-1997
(no. 27, 9 July)
Of the 22 highest-burden countries which account for 80% of all new TB
cases worldwide, the following are in Africa: Nigeria, South Africa,
Ethiopia, Democratic Republic of the Congo. Tanzania, Kenya, Uganda and
Zimbabwe. The marked upward trends in case notification rates from 1980-1997
variously reflect failing TB control (eastern Europe), the impact of
HIV (sub-Saharan Africa) and better case finding (China). For further
details, please request document WHO/CDS/CPC/TB/99.259 from WHO, CDS/CPC,
1211 Geneva 27, Switzerland. E-mail desplobainsm@who.ch
 
Progress towards measles elimination, southern Africa, 1996-1998
(no. 28, 16th July)
Despite routine measles vaccination coverage of more than 70% in Southern Africa during the early 1990s, low-level endemic transmission with periodic outbreaks of measles has continued to occur. Since 1995, 6 southern African countries (Botswana, Malawi, Namibia, South Africa, Swaziland and Zimbabwe) have launched measles elimination initiatives in accordance with the recommendations of the WHO Regional Office for Africa. Campaigns for each country were planned and implemented by national ministries of health with technical assistance from the WHO Regional Office.
A total of 23 million children were vaccinated during the catch-up campaign overall a coverage of 92% was reported in the 6 countries. The catch-up vaccination campaigns have been highly effective in reducing morbidity and mortality due to measles and none of 70 suspected measles cases tested in Botswana and Zimbabwe were laboratory confirmed, which suggests that measles transmission may have been interrupted. However to sustain the elimination initiative in the long term all WHO-recommended strategies will need to be continued.
 
Malaria in Kenya
(no. 29, 23 July)
Malaria epidemics in Kenya have been characterized since 1980 by transmission upsurges in the highlands in the western part of the country and more recently in the semi-arid north-eastern area, after the 1997 El Nino rains. These outbreaks were generally contained by case management but the strategy began to fail with increasing chloroquine resistance. In spite of epidemic preparedness activities which began in February and the delivery of antimalarial drugs to all epidemic districts in April, there has been a marked increase in the number of cases since the beginning of May in the vulnerable district with an attendant high mortality. Mortality rates are still at emergency level and they are not expected to decrease as the number of new cases continues to rise. Environmental conditions are still suitable for mosquito breeding. Malaria control activities are being coordinated in collaboration with NGOs.
 
Human African trypanosomiasis (sleeping sickness)
(no. 30, 30 July)
Sleeping sickness has a major impact on the development of rural areas by reducing the labour force and hampering production and work capacity. In countries such as Angola, Democratic Republic of the Congo, and Sudan, the operational capacity to respond to the situation has been largely surpassed. In 1995 a new WHO programme against human African trypanosomiasis was established and new objectives were defined. It is expected to achieve harmonized deployment of activities and uniformity in the tools used to take decisions and make strategic choices. For further details and more specific documentation, contact: WHO, CDS/CSR, 1211 Geneva 27, Switzerland. E-mail: janninj@who.ch
 
Progress towards polio eradication, Somalia and Southern Sudan January 1988-June 1999.
(no.30, 30 July)
Both Somalia and parts of Southern Sudan have populations living in areas where there is ongoing armed conflict and the infrastructure is poor. Under these conditions, it is difficult to achieve the first recommended strategy of polio eradication (a strong routine EPI programme), high coverage during national immunization days (NIDs) and acute flaccid paralysis surveillance. The following factors made achieving high coverage during the NIDs possible in both countries: strong partnerships between UN agencies, NGOs, local leaders and communities; the enthusiasm generated by a full-scale collaborative effort with extensive involvement of Sudanese and Somali nationals compared with health activities limited to selected areas or agencies; effective social mobilization; commitment of funds and other resources necessary to overcome the limitations of existing infrastructure.
 
Cholera 1998
(no. 31, 6 August)
The year was marked by an increase of nearly 100% in cholera cases on all continents, although there was no new major event which could have contributed to increase transmission such as population movements or wide-spread natural disasters. The global case-fatality rate (CFR) decreased slightly from 4.3% in 1997 to 3.5% in 1998. Of all continents, Africa suffered the most with 29 countries reporting cholera to WHO, and accounts for 72% of total number of cases. Major outbreaks occurred in Democratic Republic of Congo, Kenya, Mozambique, Uganda and Tanzania.
 
Malaria 1982-1997 (no. 32, 13 August)

Malaria is at present endemic in over 100 countries and territories worldwide. The lack of reliable information from many countries makes it difficult to assess annual world malaria incidence. WHO estimates that in 1998 almost 300 million clinical malaria cases occurred, with over 1 million people dying of the disease. Almost 90% of these deaths occurred in Africa South of the Sahara, where young children are the most affected. Reporting from Africa has increased considerably from an average of 5 million cases annually over the period 1962-1981 to an average of 19 million cases annually over the period 1982-1997.

Geographical information systems (GIS): mapping for epidemiological surveillance.
No. 34, 27 August.
Spatial analysis and mapping in epidemiology have a long history but until
recently their use in public health has been limited. However the late
1990s have seen a significant expansion in information and mapping
technology etc. This article gives an overview of the use of GIS in public
health. For more information on how to start using GIS and the Health
mapper contact: WHO/UNICEF Joint Programme on Data Management and Mapping,
WHO, CDS/CSR, 1211 Geneva 27, Switzerland. E-mail: surveillancekit@who.ch;
internet www:who.int/emc/healthmap/healthmap.html
 
4.3 WHO DRUG INFORMATION 1999
VOL. 13, NO. 2
WHO round table with the International Generic Pharmaceutical Alliance. This meeting, held in February 1999, offered an opportunity for both sides to address issues of public health concern including WHO essential drug concept, intectual property issues and ensuring quality control and developing good manufacturing practice within the generic industry. Short-course zidovudine in perinatal HIV transmission: more evidence and debate. Following discussion on the results of two clinical trials in Thailand and in the USA which documented a 50-68% relative efficacy of short-course zidovudine in prevention of perinatal HIV transmission in non-breast-feeding women, complementary studies from two African trials have now been published. The studies carried out in breast-feeding women in Burkina Faso and Cote d’Ivoire demonstrated a 37-38% relative efficacy. Since the African trials were stopped prematurely following the positive results of the Thailand trial, their power to address definitively the efficacy of zidovudrine in breast-feeding women is limited. The reduction of transmission in the zidovudine group was statistically significant in newborns. None the less, whether efficacy will decline with continued breastfeeding can only be determined through follow-up of infants enrolled in these studies.

Ninth International Conference of Drug Regulatory Authorities (ICDRA) The Recommendations from the Ninth Conference which took place in April in Berlin, Germany are included in this issue.

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5.0 Information from WHO-Produced Newsletters

5.1 CVI FORUM (Children’s Vaccine Initiative)
NO.18, 1999
This issue of CVI FORUM is one of the last "products" of the CVI Secretariat which will have ceased its activities by the end of this year. This special report looks at some of the products emerging from recent research. The four approaches reviewed here - DNA vaccines, transgenic plant vaccines, sugar glass vaccines and skin patch vaccines - give a taste of the possibilities and challenges offered by today’s science. To obtain a copy, please contact CVI Secretariat, WHO, 1211 Geneva 27, Switzerland.
 
5.2 SAFE MOTHERHOOD
NO. 27, 1999
Special feature: Vesico-vaginal fistula - a major cause of unnecessary and avoidable suffering.
To obtain copies of this newsletter please contact WHO/RHR, 1211 Geneva 27,
 
5.3 PROGRESS IN HUMAN REPRODUCTION AND RESEARCH
NO. 50, 1999
Advancing reproductive health through human rights and laws. Redefining
women's reproductive ill-health as a "social injustice" rather than as a
"health disadvantage" provides the legal and political basis for government
to ensure reproductive health care for all women. This issue covers the
various aspects of rights and reproductive health. To obtain copies of this
newsletter pease contact WHO/RHR, 1211 Geneva 27, Switzerland.

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6.0 New WHO Documents

The following titles are available free of charge on request from:
Document Service, World Health Organization, CH-1211 Geneva 27, Switzerland
or E-mail to: austinm@who.ch

Annotated bibliography on violence against women : a health and human rights concern.
Geneva : World Health Organization, 1999. - 45p. -
Document no. WHO/CHS/GCWH/99.2.

Child Abuse Prevention. Consultation.
(1999 : Geneva, Switzerland)
Report of the Consultation on Child Abuse Prevention, 29-31 March 1999,
WHO, Geneva. - Geneva : World Health Organization, 1999. - 54p.
Document no. WHO/HSC/PVI/99.1.

Choix des indicateurs de la sant‚ reproductive : guide … l' usage des administrateurs de district.
GenŠve : Organisation mondiale de la Sant‚ 1998. - 36p.
Document no. WHO/RHT/HRP/97.25.

Complementary feeding of young children in developing countries : a review of current scientific knowledge.
Geneva : World Health Organization, 1998. - 228p.
Document no. WHO/NUT/98.1.

Dracunculiasis or guinea-worm.
Geneva : World Health Organization, 1999. - 18p.
Document no. WHO/CDS/CEE/DRA/99.2.

Ensuring good quality vaccines throughout the world.
Geneva : World Health Organization, 1998. - 8p. + insert WHO/VSQ/97.07
Document no. WHO/VSQ/97.07 Add.1 (Rev. 1, January 1999).

Female genital mutilation : information kit.
Geneva : World Health Organization, 1999. - 16 leaves in one folder
Document no. WHO/CHS/WMH/99.11.

Female genital mutilation : programmes to date : what works and what doesn't : a review.
Geneva : World Health Organization, 1999. - 128p. + annexes
Document no. WHO/CHS/WMH/99.5.

Field manual for neonatal tetanus elimination.
Geneva : World Health Organization, 1999. - 84p.
Document no. WHO/V&B/99.14.

Guidelines for conducting a review of a national tuberculosis programme / writing committee: Jacob Kumaresan, Fabio Luelmo, Ian Smith.
Geneva : World Health Organization, 1998. - 70p.
Document no. WHO/TB/98.240.

Guidelines for safe disposal of unwanted pharmaceuticals in and after emergencies.
Geneva : World Health Organization, 1999. - 31p.
Document no. WHO/EDM/PAR/99.2.

Guidelines for the evaluation of soil-transmitted helminthiasis and schistosomiasis at community level [a guide for managers of control programmes] / A. Montresor ... [et al.].
Geneva : World Health Organization, 1998. - 45p.
Document no. WHO/CDS/SIP/98.1

It's a wormy world.
Geneva : World Health Organization, 1998. - 16p. -
Document no. WHO/CTD/SIP/98.4.

Laboratory services in tuberculosis control / writing committee: Isabel Narvaiz de Kantor ... [et al.].
Geneva : World Health Organization, 1998. - 3 pts
Document no. WHO/TB/98.258.

Options for a global fund for new vaccines.
Geneva : World Health Organization, 1999. - 42p. -
Document no. WHO/V&B/99.13.

Progress towards the elimination of Iodine Deficiency Disorders (IDD).
Geneva : World Health Organization, 1999. - 33p. + annexes - Document no.
WHO/NHD/99.4.
Removing obstacles to healthy development : World Health Orgqanization report on infectious diseases.
Geneva : World Health Organization, 1999. - 68p.
Document no. WHO/CDS/99.1.

Safe and effective use of household insecticide products : guide for the production of educational and training materials.
Geneva : World Health Organization, 1999. - 33p.
Document no. WHO/CDS/CPC/WHOPES/99.1.

Women and occupational health : issues and policy paper for the Global Commission on Women's Health / editor: Penny Kane.
Geneva : World Health Organization, 1999. - 100p.
Document no. WHO/CHS/GCWH/99.1.

Young people and substance abuse : a manual : create, use and evaluate
educational material and activities
/ edited by Maristela G. Monteiro. -
Geneva : World Health Organization, 1999. - 162p.
Document no. WHO/HSC/SAB/99.3.

The following title is available free of charge on request from: UNAIDS Information Centre.
World Health Organization, CH-1211 Geneva 27,
Switzerland or emmail to: unaids@unaids.org Web site: http://www.unaids.org

Acting early to prevent AIDS : the case of Senegal.
Geneva : UNAIDS, 1999. - 23p.
Document no. UNAIDS/99.34E.

The following title is available free of charge on request from: WHO/AFRO,
PO Box BE 773, Harare, Zimbabwe

The Work of WHO in the African Region 1999 : Annual report of the Regional
Director. 43p. Document no. AF/RC49/2

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